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Belgium-Netherlands Funding of International Trials 4 (BeNeFIT4 Call)

BeNeFIT4 Call is an international call for non-commercial practice-oriented research. It is a joint programme in which the Belgian Health Care Knowledge Centre (KCE) and ZonMw will invest 9.2 million euros together.

Who can apply

Research teams from institutions in Belgium and The Netherlands can apply to this call. Both Belgian and Dutch centres should participate, ideally with a good regional spread.

What for

The aim of the call is to provide funding for clinical trials that compare the effectiveness of existing health care interventions that are already in use for a given indication, e.g. comparisons between two medications, medical therapy versus surgery, trials investigating optimal timing of surgery etc. The research should be pragmatic and practice-oriented. The total duration of the proposed trial should be realistic and is not allowed to exceed 10 years.

What to request

There is no maximum budget per proposed trial. In total, the available budget for this call is 9.2 million euros.

When

The deadline for submission of the research outline is 28 January 2025, 14:00 h(CET).

Online information session for potential applicants (11:00 - 13:00h) 05 Nov 2024
Deadline submission Research Outline 28 Jan 2025, 14:00h
First decision letter  Medio May 2025
Online strengthening workshop – selected applicants only 11 Jun 2025
Deadline submission Full Research Proposal 02 Sep 2025, 14:00h
Prepare rebuttal 02 Oct 2025
Deadline submission rebuttal 16 Oct 2025, 14:00h
Second decision letter  End of Jan 2026
Prepare feasibility exercise, final protocol & budget, 
and response to decision letter 		 26 Jan 2026
Deadline submission feasibility report, final protocol & budget, 
and response to decision letter 		 30 Mar 2026, 14:00h
Award letter funding agencies End of May 2026

 

Expected Outcome

Scope

The aim of the call is to provide funding for clinical trials that compare the effectiveness of existing health care interventions that are already in use for a given indication, e.g. comparisons between two medications, medical therapy versus surgery, trials investigating optimal timing of surgery etc. The research should be pragmatic and practice-oriented. The total duration of the proposed trial should be realistic and is not allowed to exceed 10 years.

Partner Requests

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