Result description
Research laboratories (academic, industry) studying gut microbiota, environmental exposures (e.g. toxicologists, environmental scientists), and possibly diagnostic companies that want to measure volatile organic compounds (VOCs) from stool, dust, air or other samples.
During sample analysis of stool quickly detect microbial metabolites to characterize metabolic activity of microbiome. Likely used in the lab phase of epidemiological or clinical research on exposome–health relationships. A stool or other relevant sample is placed in a specialized device that captures and analyzes VOCs. Software then profiles the volatilome signature. The method is faster and potentially cheaper than older GC-MS or LC-MS approaches. This can be integrated into routine workflows for exposome studies. It relies on “headspace” sampling or real-time sensors to measure volatile organic compounds released by microbes. Often this is done by coupling microfluidics or sensor arrays to measure the VOC fingerprint. The technology design aims to produce a rapid readout of the compound profile without extensive sample pre-processing.
Addressing target audiences and expressing needs
- Grants and Subsidies
- Collaboration
Refine sensitivity, specificity, and coverage of the sensor arrays. Also to validate the method thoroughly across disease cohorts or environmental contexts.
- Public or private funding institutions
- Research and Technology Organisations
- Academia/ Universities
R&D, Technology and Innovation aspects
Further developments (must be done to fully validate the technology for the analysis of metabolic activity of stool sample microbiome.
The methodology can be applied in various research settings.
Result submitted to Horizon Results Platform by TAMPEREEN KORKEAKOULUSAATIO SR
