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Oxidative stress

Equipment & Facilities

BSL-2 cell culture and nanosafety laboratories

Biophotonics and Bioimaging facilities including Advance Microscopy (Zeiss LSM 780 Confocal, Witec Alpha 300R Raman, Nikon Eclipse Ti-E Fluorescence, Nikon Ti-E TIRF/dSTORM for live cell imaging, and custom-developed combined Fluorescence/AFM).

Application examples

Assessing the potential of nanomaterials to induce reactive oxygen species (ROS), which can damage cells and lead to cellular death, mutations, and other toxic effects. Support on nano-risk assessment.



Specifications and Deliverables
Suitable for organic and inorganic nanomaterials in
colloidal dispersion.
In-vitro, (CM-H2DCF-DA) assay for evaluating
nanoparticle-induced intracellular reactive oxygen
species (ROS) production according to ISO/TS

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